CHEMICALS SUMMARY PAGE

Ciprofloxacin:

Summary Information
Classification Chemicals / Complex Chemical Agents / Type:

(This chemicals section is currently predominantly used in Wildpro to link different data types and demonstrate inter-relationships. It does not contain detailed information on the chemical itself.)

Alternative Names --
Notes Information in this page has been entered to support the current volumes of Wildpro and further information will be added as new volumes are completed. This page is not intended to substitute for the manufacturer's data sheet and the information is not yet complete for all species, or for all contra-indications etc.

CAUTION: Before any pharmaceutical product is used, the manufacturer's data sheet, containing information on uses, dosage and administration, contra-indications, warnings etc., should always be consulted. It is important to remember that licensing of pharmaceutical products for use in a particular species/condition, as well as mandatory meat and milk withdrawal times for food-producing animals, varies between countries and changes with time. Withdrawal times also may vary between different pharmaceutical formulations and depending on route of administration. In the EU, the prescription cascade must be followed (see LCofC1.2H and W564.Apr05.w1); note that specific restrictions apply for food-producing animals. In the USA, FARAD may be consulted regarding residues and meat and milk withdrawal times.

  • Fluroquinolone antibiotic with a similar spectrum of activity to Enrofloxacin. (B263)
  • Bactericidal antibiotic, acts by inhibition of bacterial DNA gyrase. (B546) Bactericidal activity is concentration dependant. (B263)
  • For more information on fluoroquinolone antibiotics see Enrofloxacin.
Administration

Lagomorphs - Oryctolagus cuniculus domesticus - Domestic rabbit:

  • 5.0 - 20.0 mg/kg orally every 12 hours. (B548.w8)
  • 10 -10 mg/kg orally every 12 hours. (B548.w8)
  • 5.0 - 20.0 mg/kg orally every 12 hours. (B601.15.w15)
  • 40 mg/kg intramuscularly every 12 hours for 17 days. (B601.15.w15)
  • 10 - 20 mg/kg orally every 12 - 24 hours. (B602.41.w41)
  • Ocular 
    • (0.3% suspension, POM), one drop per affected aye every six hours; a loading dose of one drop to the affected eye every 15 minutes for four doses can be given. (B546)
    • One drop topically every 8 -12 hours. In the treatment of nasal pasteurellosis (Pasteurellosis in Lagomorphs). This maintains therapeutic levels within the tear film for at least six hours after application; tears drain into the nasal sinus. (B548.w8)
    • Two drops topically every hour for 7 - 14 hours. In the treatment of penetration injuries of the eye, with good penetration into the aqueous and vitreous humour. (B548.w8)
    • Topical, ocular drops every 8 - 12 hours. (B601.15.w15)

Ferrets - Mustela putorius furo - Ferret:

  • 5 - 15 mg/kg orally twice daily or 10 - 30 mg/kg orally once daily. "Use as enrofloxacin." (B626.App.w22)
  • 10 - 30 mg/kg orally every 12 hours. "Tablet mixes well with water and can be flavoured." (B631.21.w21)
  • 10 - 30 mg/kg orally every 24 hours. (B602.41.w41)
  • 5 - 15 mg/kg orally twice daily. (J213.3.w1)

Great Apes

  • Adult Pan troglodytes - Chimpanzee: 16 - 20 mg/kg orally twice daily. (W768.Jun2012.w1)
  • Primates: 10 - 20 mg/kg orally twice daily. Can cause arthropathy in juveniles.  (D425.3.15.w3o)

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