CHEMICALS SUMMARY PAGE

Phenobarbitone

Summary Information
Classification Chemicals / Complex Chemical Agents / Type:

(This chemicals section is currently predominantly used in Wildpro to link different data types and demonstrate inter-relationships. It does not contain detailed information on the chemical itself.)

Alternative Names Phenobarbital. (B546)
Notes Information in this page has been entered to support the current volumes of Wildpro and further information will be added as new volumes are completed. This page is not intended to substitute for the manufacturer's data sheet and the information is not yet complete for all species, or for all contra-indications etc.

CAUTION: Before any pharmaceutical product is used, the manufacturer's data sheet, containing information on uses, dosage and administration, contra-indications, warnings etc., should always be consulted. It is important to remember that licensing of pharmaceutical products for use in a particular species/condition, as well as mandatory meat and milk withdrawal times for food-producing animals, varies between countries and changes with time. Withdrawal times also may vary between different pharmaceutical formulations and depending on route of administration. In the EU, the prescription cascade must be followed (see LCofC1.2H and W564.Apr05.w1); note that specific restrictions apply for food-producing animals. In the USA, FARAD may be consulted regarding residues and meat and milk withdrawal times.

  • Barbiturate, used primarily in the control of seizures, also as a sedative. (B263)

Lagomorphs - Oryctolagus cuniculus domesticus - Domestic rabbit:

  • 1-2 mg/kg per day. For control of seizures in the absence of a specific diagnosis, but the prognosis is poor. (J15.28.w1)

Ferrets - Mustela putorius furo - Ferret

  • 2-10 mg/kg per hour as a constant rate infusion (this can be given with diazepam). For the treatment of seizures in ferrets in which blood glucose levels are normal and diazepam is not effective. (B602.11.w11) 
  • Once the seizures are under control, oral phenobarbital 1-2 mg/kg every eight to twelve hours. (B602.11.w11)
  • Phenobarbital 1 - 2 mg/kg orally two or three times a day. (J213.3.w1)

Great apes

  • In adult female Pan paniscus - Bonobo, at body weight 38-42 kg, 100 mg/kg orally twice daily has been used with some initial success. (J2.42.w1) Side effects occurred:
    • Doses of about 120 mg orally twice daily tended to result in lethargy. (J2.42.w1)
    • Abdominal bloating, painful, occurred with doses of 121.5 mg orally twice daily in one bonobo and 150 mg orally twice daily in another bonobo. (J2.42.w1)

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