CHEMICALS SUMMARY PAGE

Tylosin

Summary Information

Classification Chemicals / Complex Chemical Agents / Type:

(This chemicals section is currently predominantly used in Wildpro to link different data types and demonstrate inter-relationships. It does not contain detailed information on the chemical itself.)

Alternative Names --
Notes Information in this page has been entered to support the current volumes of Wildpro and further information will be added as new volumes are completed. This page is not intended to substitute for the manufacturer's data sheet and the information is not yet complete for all species, or for all contra-indications etc.

CAUTION: Before any pharmaceutical product is used, the manufacturer's data sheet, containing information on uses, dosage and administration, contra-indications, warnings etc., should always be consulted. It is important to remember that licensing of pharmaceutical products for use in a particular species/condition, as well as mandatory meat and milk withdrawal times for food-producing animals, varies between countries and changes with time. Withdrawal times also may vary between different pharmaceutical formulations and depending on route of administration. In the EU, the prescription cascade must be followed (see LCofC1.2H and W564.Apr05.w1); note that specific restrictions apply for food-producing animals. In the USA, FARAD may be consulted regarding residues and meat and milk withdrawal times.

A macrolide antibiotic. (B340.1.w1, B553.43.w43)

  • Well absorbed after oral administration. (B340.1.w1, B553.43.w43)
  • Metabolised in the liver and excreted via bile. (B340.1.w1, B553.43.w43)
  • Acts by inhibition of protein synthesis in the 50S ribosomal subunit. (B553.43.w43)
  • A basic compound, therefore concentrated in acidic fluids. (B340.1.w1)
  • Good activity against Gram-positive aerobic bacteria and Mycoplasma spp. (B600.4.w4, B340.1.w1); poor against anaerobes and Gram-negative bacteria. (B340.1.w1)

Lagomorphs - Oryctolagus cuniculus domesticus - Domestic rabbit:

  • "Not recommended." (B546)
  • 10 mg/kg subcutaneously or intramuscularly twice daily. (B600.4.w4)
  • 10 mg/kg orally, subcutaneously or intramuscularly every 12 hours. (B548.w8, B601.15.w15)
  • 10 mg/kg orally, subcutaneously or intramuscularly every 24 hours. (B548.w8)
  • 10 mg/kg orally or subcutaneously every 12 hours. (B602.41.w41)

Ferrets - Mustela putorius furo - Ferret:

  • 10 mg/kg orally three times daily or 5 - 10 mg/kg intravenously or intramuscularly twice daily. "Used for Gram +ve bacteria plus spirochaetes, large viruses and some Gram -ve plus mycoplasma. No toxicity indicated." (B626.App.w22)
  • 10 mg/kg subcutaneously or orally every 8 - 12 hours. (B631.21.w21)
  • 10 mg/kg orally or subcutaneously every 8 - 12 hours. (B602.41.w41)
  • 10 mg/kg orally once or twice daily. (J213.3.w1)

Great Apes

  • Primates: 2 mg/kg subcutaneously or intramuscularly once daily. (D425.3.15.w3o)

Cranes

  • 15 mg/kg subcutaneously every eight hours. (B115.8.w4 B336.20.w20) Effective against Gram-positive organisms and against some Gram-negative organisms, also against mycoplasma and chlamydial organisms. Useful in the treatment of respiratory infections. (B115.8.w4)

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