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Diseases / List of Viral Diseases / Disease description:

Simian Foamy Virus Infection

INDEX - INFORMATION AVAILABLE

GENERAL INFORMATION

SUSCEPTIBILITY, DISEASE CHARACTERISTICS & DIAGNOSIS

TREATMENT & CONTROL

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THE FOLLOWING INFORMATION IS HELD ON THE INFECTIOUS AGENT INFORMATION PAGE
Retroviridae: Simian Foamy Virus:
 

  • Virus Structure and Identification
  • Associated Host Species of Virus (Animal Types Affected) and Hazard / Risk
  • Virus Life Cycle, Transmission and Effects of Chemicals
  • Transmission and Biogeographical / Climatic Range for Virus

CLICK THIS LINK FOR Retroviridae: Simian Foamy Virus

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General and References

Disease Summary

A retrovirus infection with no apparent clinical illness. 

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Alternative Names (Synonyms)

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Disease Type

 Viral

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Infectious/Non-Infectious Agent (directly associated with the Disease)

A retrovirus, simian foamy virus.

Species/Taxa

Chemical

  • --

Physical

  • --

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References

Disease Author

Debra Bourne MA VetMB PhD MRCVS (V.w5)

Referee

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References

Detailed references are provided attached to specific sections.

ORGANISATIONS-

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ELECTRONIC LIBRARY
(Further Reading)
Click image for full contents list of ELECTRONIC LIBRARY

 

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Epidemiology and Host Susceptibility Factors

Incubation Period, Time Course and Persistence of Disease

Notes

1) INCUBATION PERIOD:

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2) DISEASE DURATION (TO RECOVERY) IN INDIVIDUAL ANIMALS:

  • Infection is persistent lifelong; virus can be detected in throat swabs many years after infection occurs. (B574.59.w59)
    • Virus was isolated from peripheral blood mononuclear cells of a human, 20 years after the animal caretaker had been bitten by an African green monkey. (J80.71.w5)

3) TIME COURSE / PERSISTENCE OF DISEASE IN A SUSCEPTIBLE POPULATION:

  • --

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Mortality / Morbidity / Susceptibility / Life stage affected

Notes

1) NUMBER OF DEATHS

  • Unlike other retrovirus infections, foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)

2) NUMBER OF ANIMALS AFFECTED

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3) EFFECTS OF AGE, SEX AND REPRODUCTIVE STATUS

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4) EFFECTS OF BODY CONDITION AND OTHER DISEASES

  • Coinfection can occur with a different SFV strain in the same host, such as SFVcpz and SFVwrc (red colobus monkey strain) in wild chimpanzees. (J80.82.w1)

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Clinical & Pathological Characteristics, and Diagnosis

Clinical Signs (by physiological system)

Overall Clinical Presentation

Unlike other retrovirus infections, foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)

  • No clinical disease occurred in infected monkeys following immunosuppression with cyclopsorin-A. (B574.59.w59)
  • A foamy virus was isolated from a 28-year-old orangutan at London Zoo which died about two years later from encephalopathy after a short illness, but was also isolated from the healthy grandson of that individual; antibodies to SFV were detected in 12 other orangutans by immunofluorescence microscopy. (J80.68.w3)

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Clinical Pathology (Testing Samples incl. Serology)

Overall Clinical Pathology findings
  • Antibodies can be detected in serum samples. (J20.237.w1, J556.11.w1)
  • Virus can be detected in throat epithelium or peripheral blood lymphocytes and proviral DNA sequences can be detected in cells of various solid organs, or lymphocytes. (J556.11.w1)

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Pathological Findings (by anatomical system)

Notes
  • Not applicable; foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)

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Diagnostic Criteria

General Indicative Signs
  • Not applicable; foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)
Definitive Diagnosis
  • Infection is indicated by: SFV in either throat epithelium or peripheral blood lymphocytes; presence of proviral DNA sequences in cells (of various solid organs, or lymphocytes); appropriate antibodies which can be detected by Western blot, radioimmunoprecipitation assay or immunofluorescence assay. (J556.11.w1)
  • For further information on different serological tests and virus identification see: Retroviridae- Simian Foamy Virus

Similar Diseases

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CLICK THE LINKS FOR OVERVIEWS of management techniques available
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Treatment and Control

Specific Medical Treatment (Antiserum, Antidote, Anti-(viral/bacterial/fungal) etc.)

Specific Medical Treatment
  • Not applicable; foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)
CLICK THE LINKS FOR OVERVIEWS of management techniques available
  • No specific techniques described

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General Nursing and Surgical Techniques

Nursing and Supportive Care
  • Not applicable; foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)
Surgical Treatment
  • Not applicable
CLICK THE LINKS FOR OVERVIEWS of management techniques available

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Vaccination & Prophylactic Treatment

Vaccination
  • Not applicable; foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)
Prophylactic Treatment
  • Not applicable; foamy virus infections are not associated with any known clinical disease. (B574.59.w59, J80.73.w3, J98.355.w1 J543.35.w1)
CLICK THE LINKS FOR OVERVIEWS of management techniques available

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Environmental and Population Control Measures

General Environment Changes, Cleaning and Disinfection
  • Not applicable
CLICK THE LINKS FOR Technique Descriptions, if available
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Population Control Measures
  • Not applicable
CLICK THE LINKS FOR Technique Descriptions, if available
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Isolation and Quarantine
  • Not applicable
CLICK THE LINKS FOR Technique Descriptions, if available
  • --
CLICK THE LINKS FOR OVERVIEWS of management techniques available
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Authors & Referees

Authors Debra Bourne MA VetMB PhD MRCVS (V.w5)
Referee  

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