DISEASE SUMMARY PAGE

Poliomyelitis in Great Apes

Summary Information

Diseases / List of Viral Diseases / Disease summary
Alternative Names Polio
Disease Agents Poliovirus, an enterovirus within the Picornaviridae. (B336.39.w39, D390.48.w48)
Infectious Agent(s) --
Non-infectious Agent(s) --
Physical Agent(s) --
General Description
Clinical signs
  • Can be asymptomatic. (B336.39.w39, D390.48.w48)
  • With disseminated disease, paresis, paraplegia and sometimes death. (B336.39.w39)
    • Fever, headache, gastro-intestinal signs, nuchal rigidity and paralysis may develop. (D390.48.w48)
Incubation
  • Seven to 14 days. (D390.48.w48)
Morbidity/Mortality
  • Epizootics have occurred in wild great apes. (B336.39.w39)
Further Information
Transmission
  • Faeco-oral. (B336.39.w39)
    • Note: Epizootics in wild great apes have generally been seen associated with disease in local human populations. (B336.39.w39)
Occurrence
  • Great apes, also Colobus abyssinicus kikuyensis. (D390.48.w48)
Diagnosis
  • Clinical signs lead to presumptive diagnosis. (B336.39.w39)
  • Virus detection: in tissue culture, by indirect immunofluorescence, PCR, antigen-capture PCR or hybridization. (D390.48.w48)
  • Seroconversion - two serum samples taken 3-4 weeks apart, tested by neutralisation assay or isotype-specific capture ELISA. (D390.48.w48)
Prevention
  • Vaccination - trivalent parenteral vaccine. (B336.39.w39)
Associated Techniques
Host taxa groups /species
Author Dr Debra Bourne MA VetMB PhD MRCVS (V.w5)
Referees  

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