DISEASE SUMMARY PAGE

Hemlock (Conium maculatum) and Thorn apple (Datura stramonium) Toxicity in Elephants

Summary Information
Diseases / List of Toxic Diseases / Disease summary
Alternative Names
  • Hemlock (Conium maculatum) and thorn apple (Datura stramonium) toxicosis.
  • Hemlock (Conium maculatum) and thorn apple (Datura stramonium) poisoning.
Disease Agents Hemlock (Conium maculatum) and thorn apple (Datura stramonium).
  • Toxic agents in Datura stramonium include atropine and other atropine-like chemicals - scopolamine and hyoscine. (B450.8.w8, B455.w2)
Infectious Agent(s)
  • Hemlock (Conium maculatum) and thorn apple (Datura stramonium)
Non-infectious Agent(s)  
Physical Agent(s) --
General Description Clinical signs
  • A captive female elephant (Elephas maximus - Asian Elephant) showed apparent blindness with associated stumbling and falling, depression, trunk paresis, prolapse of the nictitating membranes across the eyeballs and mydriasis with no pupil response to bright light. (J3.110.w6)
  • Salivation was decreased and the tongue became dry. (J3.110.w6)
  • On clinical examination the respiration and heart rate were normal, but respiration was considered shallower than normal and the heart beat decreased in strength. (J3.110.w6)
  • Signs had started at 11 am; by 16.30 the same day the elephant appeared normal except for mydriasis (considered probably due to the atropine given in treatment), and was eating. (J3.110.w6)
  • No defecation occurred until early the following morning (the incident having occurred mid-morning). (J3.110.w6)

Incubation

  • Signs were recorded approximately 45 minutes after the elephant had arrived at a wasteland area where hemlock (Conium maculatum) and thorn apple (Datura stramonium) were consumed. (J3.110.w6)
Further Information Note: Although there was evidence that both plants were ingested, the clinical signs and rapidity of onset described suggest Datura stramonium rather than Conium maculatum poisoning. (B455.w2)

Treatment:

  • Atropine sulphate: 16 mg intramuscularly was given in this case. (J3.110.w6); 
    • Note: Atropine is the toxic agent found in Datura, furthermore atropine is not used to treat Conium toxicity. This animal survived despite the treatment. (B450.8.w8)
  • A "large dose" [not specified] short acting corticosteroid. (J3.110.w6)
Associated Techniques
Host taxa groups /species Further information on Host species has only been incorporated for species groups for which a full Wildpro "Health and Management" module has been completed (i.e. for which a comprehensive literature review has been undertaken). Host species with further information available are listed below:

(List does not contain all other species groups affected by this disease)

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